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Antibiotics in dental care

Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Topics
Tooth injury: avulsion and replantation

Tooth injury: avulsion and replantation

Immediate care

In avulsion, the tooth is completely displaced from its socket. Arrange immediate dental care. The KNMT aims for assessment within 30 to 60 minutes. Check whether the tooth is permanent or primary. Do not replant a primary tooth.

Hold a permanent tooth by the crown only. If visibly contaminated, rinse it briefly and gently without touching or scrubbing the root. Replant as soon as possible if safe and feasible. If immediate replantation is not possible, keep the tooth in milk for transport.

Replantation, splinting and follow-up

Record the time out of the mouth, the time the tooth was dry and the storage medium. Assess root development, the socket and any associated injuries. After replantation, confirm the tooth's position clinically and radiographically.

The Dutch splinting instructions usually advise a flexible splint for three weeks after avulsion. Adapt the splinting plan if there is additional alveolar injury. Plan clinical and radiographic follow-up, and decide on endodontic management based on root development and healing.

Antibiotics and tetanus

Assess contamination of the tooth and wound. KIMO notes that the Dutch Dental Trauma Guide reserves immediate systemic antibiotics for signs of contamination. Follow the injury-specific protocol for the indication and choice of medicine.

Check tetanus vaccination status. If in doubt, consult the doctor about the tetanus prophylaxis required.

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AB Kader

Antibiotics in dental care

Principles · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Principles

Principles

Dental professionals · adults

Indications for antibiotics

An odontogenic infection with spread or systemic red flags may require antibiotics in addition to source control. Adjunctive treatment may also be considered in selected cases of severe or rapidly progressing periodontitis.

Prophylaxis aims to prevent a complication around a procedure. There are separate indications in implantology and for patients with endocarditis risk, MRONJ risk or certain oncology-related circumstances. A single prophylactic dose is not a treatment course.

Diagnostics and choice of antibiotics

Diagnose and treat the local cause. Discuss the expected benefits, adverse effects and risk of resistance. Choose an antibiotic with a spectrum appropriate to the indication.

Check previous allergic reactions, recent antibiotic use, comorbidities, renal and hepatic function, and the current medication list. Follow the protocol for the risk group and consult the treating specialist if needed. If the extent of an odontogenic infection is uncertain, consult or refer to an oral and maxillofacial surgeon.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Algemene principes van rationeel antibioticumgebruik

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · richtlijntekst 3 maart 2025

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/algemene-principes-van-rationeel-antibioticumgebruik/

Linked passages

  • Algemene principes van rationeel antibioticumgebruik
  • Indicatie voor antibiotica; Empirische therapie; Profylaxe

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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Linked passages

  • Aanbevelingen

Indicatiestelling antibioticumgebruik in de mondzorg — Parodontitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 4

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  • Aanbevelingen

Indicatiestelling antibioticumgebruik in de mondzorg — Implantologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 1

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  • Aanbevelingen

Indicatiestelling antibioticumgebruik in de mondzorg — Preventie van MRONJ

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 8

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Linked passages

  • Aanbevelingen

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

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2025-12-18
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https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Prevention and prophylaxis; Table 1, p. S2–S3

Extramurale mondzorg tijdens en na kankerbehandeling

KIMO — Kennisinstituut Mondzorg · In werking 15 juni 2026 · PDF-tekst 28 maart 2025 · KNMT-aanvaarding 20 april 2026

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2026-06-15
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https://www.hetkimo.nl/wp-content/uploads/2026/06/KPR-EMK-richtlijn-28032025.pdf

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  • Algemene aspecten; Tabel 1, p. 16–17
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AB Kader

Antibiotics in dental care

Odontogenic infection or abscess · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Odontogenic infection or abscess

Adults with an odontogenic infection or abscess

source control and assessment

Antibiotics are generally not indicated for a localised infection or abscess. Treat the local cause and drain the abscess if its location and margins allow.

Consider adjunctive antibiotics for a spreading infiltrate or red flags after assessing severity and the need for referral.

Dosage in adults

If antibiotic treatment is chosen: amoxicillin 500 mg by mouth three times daily for five days if the clinical response is good. For amoxicillin allergy, KIMO lists clindamycin 600 mg by mouth three times daily for five days.

Assess the clinical course after source control. If the response is inadequate, reassess the diagnosis, source control and need for referral before changing or renewing the course.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Uitgangsvraag 7; Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond: alarmsymptomen en verwijzing
  • Aanbevelingen; uitgezonderde patiëntgroepen

Amoxicilline

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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Linked passages

  • Contra-indicaties

Clindamycine (systemisch)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/clindamycine__systemisch_

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  • Waarschuwingen en voorzorgen

Spoedlijst bij Beleid rondom spoedoperaties · MKA-chirurgie

Nederlandse Vereniging voor Mond-, Kaak- en Aangezichtschirurgie · 2024 · Bijlage 5

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  • Categorie 1: snel progressief logeabces met bedreigde luchtweg
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AB Kader

Antibiotics in dental care

Apical periodontitis · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Apical periodontitis

Adults with periapical granuloma or apical periodontitis

Local treatment

Routine antibiotics are not indicated for a periapical granuloma or apical periodontitis. Provide endodontic treatment or retreatment, with apical surgery if needed. Extraction is an alternative.

If infection is spreading or there are systemic signs, see “Odontogenic infection or abscess”.

Irreversible pulpitis in adults

Antibiotics are not indicated for pain from irreversible pulpitis. Treat the pulp locally and provide appropriate pain relief. If there are signs of spreading or systemic infection, follow the guidance for odontogenic infection.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen

Indicatiestelling antibioticumgebruik in de mondzorg — Periapicaal granuloom/parodontitis apicalis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 6

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Linked passages

  • Uitgangsvraag 6; Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond
  • Aanbevelingen; uitgezonderde patiëntgroepen

Richtlijn endodontische diagnostiek en behandeling

Nederlandse Vereniging voor Endodontologie · Update 2025 · versie 1.0

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  • Hoofdstuk 9: Acute klachten en pijnmanagement; Aanbevelingen, p. 220
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Antibiotics in dental care

Periodontitis and necrotising conditions · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Periodontitis and necrotising conditions

Adults · antibiotics only as an adjunct to periodontal treatment

Indications for additional antibiotics

Consider adjunctive antibiotics for generalised advanced to very advanced rapidly progressing periodontitis with relatively little plaque and calculus, documented rapid bone loss, or necrotising periodontal disease with systemic symptoms.

This is not routine treatment. It requires comprehensive supra- and subgingival treatment, professional cleaning, good motivation and self-care, and discussion of the benefits and risks.

choice of medicine and dosage in adults

When antibiotics are indicated, the preferred monotherapy is metronidazole 500 mg by mouth three times daily for seven days.

Consider combining amoxicillin with metronidazole when well-delivered periodontal treatment gives an inadequate response despite good self-care, or in adults aged 18 to 20 years with a molar–incisor pattern. KIMO gives 500 mg amoxicillin and 500 mg metronidazole, each three times daily for seven days, as an example.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Parodontitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 4

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/therapeutisch-antibioticumgebruik-parodontitis/

Linked passages

  • Uitgangsvraag 4; Aanbevelingen
  • Aanbevelingen
  • Aanbevelingen; uitgezonderde patiëntgroepen
  • Aanbevelingen: monokuur en complexe situaties
  • Aanbevelingen: complexe situaties

Metronidazol (oraal)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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  • Interacties
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AB Kader

Antibiotics in dental care

Peri-implantitis and mucositis · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Peri-implantitis and mucositis

Adults with peri-implant inflammation

No standard empirical course

Start with mechanical cleaning and oral hygiene instruction for peri-implant mucositis and peri-implantitis. In mucositis, antibiotics provide no additional benefit over mechanical cleaning.

No added benefit has been established for systemic antibiotics with surgical or non-surgical treatment of peri-implantitis. If antibiotics are considered, take into account microbiology, resistance, disease severity and immune status. Arrange surgical follow-up if the response is inadequate.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Peri-implantitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 5 · verwijsmodule

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Linked passages

  • Uitgangsvraag 5: verwijzing
  • Verwijzing naar richtlijn Peri-implantaire infecties

Peri-implantaire infecties — behandeling van mucositis en peri-implantitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2018 · richtlijnsamenvatting 4 en 5

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  • Richtlijnsamenvatting 4 en 5
  • Richtlijnsamenvatting 4 en 5: niet-chirurgische en chirurgische behandeling
  • Richtlijnsamenvatting 5
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AB Kader

Antibiotics in dental care

Implantology and bone augmentation · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

Implantology and bone augmentation

Adults · general implant indication. Separate risk protocols still apply

Indications for prophylaxis

Discuss prophylaxis for bone augmentation, with or without implant placement, including sinus floor elevation, guided bone regeneration and immediate implant placement. Previous implant failure, limited options if a new implant fails, or an increased risk of impaired wound healing, such as with diabetes, may also warrant consideration.

Be cautious about prophylaxis for uncomplicated implant placement without additional risk factors or augmentation, soft tissue surgery, and ridge preservation using only a bone substitute. Discuss the expected benefits and harms.

Single dose before the procedure

If prophylaxis is chosen, give a single dose of amoxicillin 2 g by mouth 30 to 60 minutes before the procedure. For amoxicillin allergy, KIMO lists a single dose of clindamycin 600 mg by mouth.

Extended prophylaxis is not indicated. For unusually long procedures, consult the perioperative protocol.

Sources

Amoxicilline

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/a/amoxicilline

Linked passages

  • Contra-indicaties

Clindamycine (systemisch)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

Publication
Niet vermeld
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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/clindamycine__systemisch_

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  • Waarschuwingen en voorzorgen

Indicatiestelling antibioticumgebruik in de mondzorg — Implantologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 1

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/uitgangsvraag-1/

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  • Uitgangsvraag 1; Aanbevelingen; Achtergrond
  • Aanbevelingen
  • PICO: uitgesloten patiëntgroepen
  • Aanbevelingen; Achtergrond: timing en verlengde profylaxe
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AB Kader

Antibiotics in dental care

Endodontic treatment · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

Endodontic treatment

Adults undergoing endodontic surgery, including apical surgery

Only when a risk of complications has been established

Restrict prophylaxis for endodontic procedures. Consider it only where there is a real risk of infectious complications.

This general recommendation does not apply to an existing infection or abscess and does not specify a universal regimen. Assess separately whether endocarditis or MRONJ prophylaxis is needed.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Endodontologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 2

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/antibioticaprofylaxe-endodontologie/

Linked passages

  • Uitgangsvraag 2; PICO; Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond
  • PICO: uitgezonderde patiëntgroepen; immuuncompromittering wordt door behandelende beroepsgroepen beoordeeld
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Antibiotics in dental care

Third molar removal · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

Third molar removal

Adults · surgical removal of third molar

No routine prophylaxis

Do not give antibiotics routinely around third molar removal. A higher risk of postoperative complications or a separate indication for prophylaxis may justify an exception.

KIMO 2025 refers to the aftercare module of the 2020 third molar guideline, which gives no general recommendation for the drug, dose or duration. Assess any indication for endocarditis or MRONJ prophylaxis separately.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Derde molaar

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 3 · verwijsmodule

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Linked passages

  • Uitgangsvraag 3: verwijzing
  • Verwijzing naar richtlijn Derde molaar

Derde molaar — Nazorg

KIMO — Kennisinstituut Mondzorg · Richtlijn 2020 · §5.1 Antibiotica

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  • Nazorg 5.1 Antibiotica
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Antibiotics in dental care

Endocarditis prophylaxis · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

Endocarditis prophylaxis

Adults · high-risk patient and relevant dental procedure

Cardiac risk and type of procedure

Prophylaxis is for a high-risk patient undergoing a relevant procedure. The NVVC lists previous endocarditis, a prosthetic valve, a ventricular assist device and congenital heart disease such as unrepaired cyanotic defects or palliative shunts, conduits and other prostheses. The NHG also specifies repair of an ASD, VSD or patent ductus arteriosus using prosthetic material through six months after repair, and a residual shunt that may impair endothelialisation. Confirm the precise cardiac diagnosis and current specialist plan.

The NHG lists gingival manipulation, endodontic instrumentation beyond the apical foramen, extraction or root removal, and oral surgery, including abscess incision, periodontal surgery and implant surgery. Local anaesthesia, intraoral radiographs and routine work on orthodontic appliances are not indications in themselves.

Dosage in adults

For adults, the NVVC recommends amoxicillin 2 g by mouth as first choice and clindamycin 600 mg by mouth for confirmed penicillin or ampicillin allergy. The NHG treatment guideline specifies a single oral dose 30 to 60 minutes before the procedure. It also lists clindamycin if penicillin has been used in the previous seven days. If penicillin was used during that period, agree the choice of medicine with the cardiology team.

The NVVC lists ceftriaxone 1 g intravenously as an alternative. It requires a separate specialist and allergy assessment and appropriate administration. Do not substitute it automatically in severe beta-lactam allergy.

Sources

Clindamycine (systemisch)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/clindamycine__systemisch_

Linked passages

  • Waarschuwingen en voorzorgen

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

Publication
2025-12-18
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Prevention and prophylaxis; Table 1, p. S2–S3
  • Prevention and prophylaxis: high-risk versus intermediate-risk, p. S2
  • Prevention and prophylaxis, p. S2–S3
  • Table 1; toelichting Nederlandse afwijking van ESC 2023, p. S3
  • Table 1 en begeleidende tekst, p. S3

NHG-Behandelrichtlijn Endocarditisprofylaxe

Nederlands Huisartsen Genootschap · auteursversie via NVMKA · Versie 1.0 · november 2016 · oorspronkelijke tekst; huidige NHG-webrevisie niet verifieerbaar

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2016-11
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https://www.nvmka.nl/wp-content/uploads/2022/07/2016-NHG-Behandelrichtlijn-Endocarditisprofylaxe-1.pdf

Linked passages

  • Risicopatiënten, ingrepen en orale timing, p. 4–6
  • Hoogrisicopatiënten en hoogrisico-ingrepen; Geen indicaties, p. 4–5
  • Medicamenteuze behandeling: Bij tandheelkundige behandeling, p. 6

Ceftriaxon

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/ceftriaxon

Linked passages

  • Contra-indicaties

Essential messages from the 2023 ESC Guidelines for the management of endocarditis

European Society of Cardiology · ESC 2023 · Essential messages

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https://www.escardio.org/static-file/Escardio/Guidelines/Products/Slide%20sets/2023%20Gls/Essential%20Messages_2023%20Endocarditis.pdf

Linked passages

  • Key messages, punt 1: hoogrisicogroepen en profylaxe bij oro-dentale ingrepen
an app by mondarium
AB Kader

Antibiotics in dental care

MRONJ risk and bone medication · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

MRONJ risk and bone medication

Adults with current or previous use of antiresorptive medicines or angiogenesis inhibitors

Procedure, medicine and duration of use

Ask about medicines used previously as well. Antibiotic prophylaxis is not indicated for endodontic or periodontal treatment without bone manipulation.

For extraction, implant or periodontal procedures involving bone manipulation, and apical surgery, KIMO advises against prophylaxis after less than 24 months of oral antiresorptive treatment or less than one year of intravenous antiresorptive treatment. Prophylaxis is indicated after 24 to 36 months of oral treatment.

Use extreme caution if the patient has taken oral antiresorptives for at least 36 months, received intravenous antiresorptives for at least one year or uses angiogenesis inhibitors. If the procedure is unavoidable, treatment in secondary care with prophylaxis is preferred.

choice of medicine and individual dosing

When prophylaxis is indicated, KIMO lists amoxicillin as the preferred agent and clindamycin for amoxicillin allergy. There is no consensus on the dose. Document the medicine, dose, timing and duration in the individual treatment plan.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Preventie van MRONJ

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 8

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/preventie-van-mronj-patienten-met-botafbraakremmende-medicatie-of-angiogeneseremmers/

Linked passages

  • Uitgangsvraag 8; PICO; Aanbevelingen
  • Aanbevelingen: ingreep en blootstellingsduur
  • Aanbevelingen; Achtergrond: botafbraakremmende medicatie
  • Aanbevelingen: middelkeuze en ontbreken doseringsconsensus
  • PICO: radiotherapie, immuuncompromittering en endocarditisprofylaxe afzonderlijk beoordeeld

Extramurale mondzorg tijdens en na kankerbehandeling

KIMO — Kennisinstituut Mondzorg · In werking 15 juni 2026 · PDF-tekst 28 maart 2025 · KNMT-aanvaarding 20 april 2026

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2026-06-15
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https://www.hetkimo.nl/wp-content/uploads/2026/06/KPR-EMK-richtlijn-28032025.pdf

Linked passages

  • MRONJ: medicatie en toedieningswegen, p. 28–30
an app by mondarium
AB Kader

Antibiotics in dental care

Cancer treatment and immune function · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

Cancer treatment and immune function

Adults · cancer-related myelosuppression or previous head and neck radiotherapy

Prophylaxis in cancer-related myelosuppression

Where possible, defer elective treatment until blood counts have recovered sufficiently. For urgent extractions or oral surgery during or after myelosuppressive cancer treatment, KIMO lists antibiotic prophylaxis for a neutrophil count below 1.5 × 10⁹/L, in consultation with the medical oncologist or haematologist.

A neutrophil count of 1.5 × 10⁹/L or higher does not indicate prophylaxis on this basis. A central line alone is also insufficient. Assess additional risk factors and the required treatment setting. The guideline gives no universal choice of antibiotic, dose or duration here.

After head and neck radiotherapy

If bone manipulation is planned in an area that received at least 25 Gy, consult an oral and maxillofacial surgeon or special dental care centre beforehand, preferably at a head and neck oncology centre. This also applies to urgent procedures and regardless of the time since radiotherapy. The need for consultation does not itself indicate antibiotic use.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Endodontologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 2

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/antibioticaprofylaxe-endodontologie/

Linked passages

  • PICO: immuuncompromittering

Extramurale mondzorg tijdens en na kankerbehandeling

KIMO — Kennisinstituut Mondzorg · In werking 15 juni 2026 · PDF-tekst 28 maart 2025 · KNMT-aanvaarding 20 april 2026

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2026-06-15
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https://www.hetkimo.nl/wp-content/uploads/2026/06/KPR-EMK-richtlijn-28032025.pdf

Linked passages

  • Algemene aspecten; Tabel 1; Hoofd-halsradiotherapie, p. 16–17, 35–36
  • Algemene aspecten: aandachtspunten; Tabel 1 en toelichting, p. 16–17
  • Algemene aspecten; Tabel 1, p. 16–17
  • Hoofd-halsradiotherapie: aandachtspunten en aanbeveling, p. 35–36
an app by mondarium
AB Kader

Antibiotics in dental care

Amoxicillin · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Amoxicillin

Use the indication to guide safe medicine selection. See the relevant indication and medicine information.

Role in dental care

KIMO lists amoxicillin for odontogenic infection when antibiotics are indicated and for selected implant prophylaxis. In complex periodontitis it may be considered together with metronidazole. Dutch guidance also lists a dose of oral amoxicillin for endocarditis prophylaxis. Dose and duration vary by indication.

If MRONJ prophylaxis is indicated, KIMO lists amoxicillin as the preferred agent. There is no consensus on the dose.

Checks before prescribing

Do not use in penicillin hypersensitivity or after a severe reaction to another beta-lactam antibiotic. The FK also lists infectious mononucleosis and lymphocytic leukaemia as contraindications.

Check renal function and interactions, including those with vitamin K antagonists, methotrexate, allopurinol and probenecid. Consult the full monograph for dose adjustment, pregnancy, breastfeeding and excipients.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen

Amoxicilline

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/a/amoxicilline

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  • Volledige preparaattekst; Contra-indicaties; Interacties; Doseringen
  • Contra-indicaties; Interacties; Doseringen; Zwangerschap; Lactatie
  • Waarschuwingen en voorzorgen

Indicatiestelling antibioticumgebruik in de mondzorg — Parodontitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 4

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/therapeutisch-antibioticumgebruik-parodontitis/

Linked passages

  • Aanbevelingen: complexe situaties

Indicatiestelling antibioticumgebruik in de mondzorg — Implantologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 1

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  • Aanbevelingen

Indicatiestelling antibioticumgebruik in de mondzorg — Preventie van MRONJ

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 8

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/preventie-van-mronj-patienten-met-botafbraakremmende-medicatie-of-angiogeneseremmers/

Linked passages

  • Aanbevelingen

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

Publication
2025-12-18
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https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Table 1, p. S3
an app by mondarium
AB Kader

Antibiotics in dental care

Clindamycin · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Clindamycin

This is a specialist option for systemic treatment in adults. It is not an automatic substitute in patients with a penicillin allergy.

Use in penicillin allergy

KIMO lists clindamycin for patients allergic to amoxicillin with odontogenic infections and for selected indications for implant prophylaxis or MRONJ prophylaxis. For adult endocarditis prophylaxis, the NVVC retains clindamycin for confirmed penicillin allergy. The 2023 ESC guideline removed clindamycin for this indication. Dose, frequency and duration depend on the indication. There is no consensus on dosing for MRONJ prophylaxis.

Contraindications and precautions

Lincomycin hypersensitivity is a contraindication. Check for a history of colitis, renal and hepatic impairment, and neuromuscular disorders. Clindamycin can also cause severe reactions in patients with penicillin allergy.

Do not combine with erythromycin. For vitamin K antagonists, monitor PT/INR. Check for other interactions, including with neuromuscular blockers, CYP3A4 inhibitors or inducers, and ciclosporin. Consult the full FK monograph, including its advice on pregnancy and breastfeeding.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

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  • Aanbevelingen

Clindamycine (systemisch)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/clindamycine__systemisch_

Linked passages

  • Volledige systemische preparaattekst; Contra-indicaties; Interacties; Waarschuwingen en voorzorgen
  • Contra-indicaties; Interacties; Waarschuwingen en voorzorgen; Zwangerschap; Lactatie
  • Waarschuwingen en voorzorgen; Interacties
  • Waarschuwingen en voorzorgen: Overgevoeligheid

Indicatiestelling antibioticumgebruik in de mondzorg — Implantologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 1

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/uitgangsvraag-1/

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  • Aanbevelingen

Indicatiestelling antibioticumgebruik in de mondzorg — Preventie van MRONJ

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 8

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/preventie-van-mronj-patienten-met-botafbraakremmende-medicatie-of-angiogeneseremmers/

Linked passages

  • Aanbevelingen

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

Publication
2025-12-18
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Niet vermeld
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2026-11-10
Open official source (new tab)

https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Table 1 en toelichting, p. S3
an app by mondarium
AB Kader

Antibiotics in dental care

Metronidazole · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Metronidazole

Adults · Oral use

Targeted use in periodontitis

When adjunctive antibiotics are indicated in selected cases of periodontitis, KIMO prefers metronidazole alone: 500 mg by mouth three times daily for seven days. The combination with amoxicillin is reserved for selected complex cases.

Interactions and organ function

Do not use in nitroimidazole hypersensitivity. Check in particular for interactions with vitamin K antagonists, lithium, disulfiram and ciclosporin. The FK also lists interactions with busulfan and fluoropyrimidines. Assess further if the patient has hepatic impairment or a neurological disorder.

The manufacturer advises avoiding alcohol, including alcohol-containing medicines, during treatment and for at least 48 hours after the last dose. Consult the full monograph for renal and hepatic function, pregnancy and breastfeeding.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Parodontitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 4

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/therapeutisch-antibioticumgebruik-parodontitis/

Linked passages

  • Aanbevelingen: monokuur en complexe situaties

Metronidazol (oraal)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/m/metronidazol__oraal_

Linked passages

  • Volledige orale preparaattekst; Contra-indicaties; Interacties; Waarschuwingen en voorzorgen
  • Contra-indicaties; Interacties; Waarschuwingen en voorzorgen; Zwangerschap; Lactatie
  • Waarschuwingen en voorzorgen
an app by mondarium
AB Kader

Antibiotics in dental care

Amoxicillin/clavulanic acid · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Amoxicillin/clavulanic acid

Adults · reserved option. Do not routinely broaden antibiotic cover

Severe dental abscess with spreading cellulitis

The FK lists spreading cellulitis with severe dental abscess as an indication. It advises reserving this combination for pathogens resistant to amoxicillin because they produce beta-lactamases that are susceptible to inhibition by clavulanic acid.

This combination is not a routine choice for odontogenic infections. If treatment has no effect, reassess source control and severity before changing treatment. Agree on broader treatment or specialist management if needed.

Allergy, liver and interactions

Do not use in severe penicillin or cephalosporin hypersensitivity, or in patients who previously had jaundice, hepatic impairment or AGEP caused by this combination. Check renal function and product strength. Avoid use if infectious mononucleosis is suspected or confirmed.

Check for interactions with methotrexate, vitamin K antagonists, mycophenolate, allopurinol and probenecid, among others. Consult the FK monograph for the full interactions list, dosing, pregnancy and breastfeeding.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen: eerste keuze en MKA-overleg

Amoxicilline/clavulaanzuur

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/a/amoxicilline_clavulaanzuur

Linked passages

  • Volledige preparaattekst; Advies; Indicaties; Contra-indicaties; Interacties
  • Advies; Indicaties; Doseringen: algemeen bij infecties
  • Advies; Indicaties
  • Contra-indicaties; Interacties; Doseringen; Waarschuwingen en voorzorgen
  • Waarschuwingen en voorzorgen

Augmentin 500 mg/125 mg, filmomhulde tabletten · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 09840

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2026-09-09
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https://www.geneesmiddeleninformatiebank.nl/smpc/h09840_smpc.pdf

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  • Rubrieken 4.1–4.4: indicaties, dosering, behandelduur, nierfunctie en contra-indicaties
an app by mondarium
AB Kader

Antibiotics in dental care

Ceftriaxone · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Ceftriaxone

Adults · specialist intravenous option for endocarditis prophylaxis

Specialist endocarditis prophylaxis

The NVVC lists ceftriaxone 1 g intravenously as an alternative regimen for endocarditis prophylaxis in high-risk dental procedures.

Assess the indication, hypersensitivity risk and route of administration separately. For penicillin allergy, use ceftriaxone only after that assessment. Section 4.1 of this SmPC does not list dental endocarditis prophylaxis as an indication.

Beta-lactam allergy and infusion safety

Do not use in patients with cephalosporin hypersensitivity or a previous severe reaction to other beta-lactam antibiotics. Check the full FK monograph for combined hepatic and renal impairment, interactions, pregnancy, breastfeeding and administration.

Do not administer at the same time as intravenous calcium-containing solutions because of precipitation risk. For sequential administration in adults, follow the specified infusion-line precautions.

Sources

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

Publication
2025-12-18
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Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Prevention and prophylaxis; Table 1, p. S2–S3
  • Table 1: Revised prophylactic antibiotic regime for high-risk dental procedures, p. S3

Ceftriaxon

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/ceftriaxon

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  • Volledige preparaattekst; Contra-indicaties; Interacties; Waarschuwingen en voorzorgen
  • Contra-indicaties; Interacties; Doseringen: Toediening; Waarschuwingen en voorzorgen
  • Waarschuwingen en voorzorgen

Ceftriaxon Navamedic 1 g · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 134134 · 1 g, poeder voor oplossing voor injectie/infusie

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https://www.geneesmiddeleninformatiebank.nl/smpc/h134135_smpc.pdf

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  • Rubrieken 4.1–4.4 en 6.5–6.6: geregistreerde indicaties, intraveneuze toediening, contra-indicaties en flacon
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AB Kader

Antibiotics in dental care

Paediatric antibiotics · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Children

Paediatric antibiotics

Children younger than 18 years. The selected regimen specifies the age limits and any weight limit for the calculation.

source control and assessment

Treat the local cause in pulpitis or a localised abscess without spread or systemic signs. Consider systemic antibiotics only if the infection is spreading or systemic signs justify them.

Assess the cause and arrange drainage or other definitive treatment. Consult an oral and maxillofacial surgeon or paediatrician if the severity or suitability of oral treatment is uncertain.

Odontogenic infection · amoxicillin

This regimen applies to non-severe odontogenic infection for which oral antibiotics are indicated. For paediatric dosing, KIMO refers to the Kinderformularium. The product information gives a wider dose range for dental abscess with spreading cellulitis.

For non-severe bacterial infections, the Kinderformularium lists oral amoxicillin at 50 mg/kg/day in three divided doses, up to 1,500 mg/day.

The calculator for odontogenic infection is available from 3 months of age and for a weight below 40 kg. Assess management individually in severe infection, penicillin allergy or when a dose adjustment is needed. The EAPD guidance describes reassessment after two to three days and treatment for up to five days, depending on source control and clinical recovery.

Endocarditis prophylaxis

Confirm both a high-risk cardiac condition and a high-risk dental procedure. Follow the current cardiology plan. Amoxicillin is the usual first choice when oral prophylaxis is appropriate.

The Kinderformularium lists a single oral dose of 50 mg/kg amoxicillin, up to 2 g, 30 to 60 minutes before the procedure.

For confirmed penicillin allergy, the EAPD lists azithromycin or clarithromycin as an oral alternative. Use either only after the paediatric cardiologist confirms the indication and choice of medicine. Give a single dose of 15 mg/kg, up to 500 mg according to the ESC, 30 to 60 minutes before the procedure. This use is off-label for both medicines. Assess QT risk and check current medicines for interactions.

The Kinderformularium lists a single oral clindamycin dose of 20 mg/kg, up to 600 mg, 30 to 60 minutes before the procedure. The NVVC recommendation for clindamycin applies to adults. The older NHG treatment guideline uses different weight bands. Agree the choice and dose with the cardiology team in line with the current plan, including after recent penicillin use.

Dosage and prescribing

Use a recently measured body weight in kg. Before prescribing, check the indication, age, allergies, renal and hepatic function, and interactions. The calculator checks for outlying age and weight values. If weight remains outside the check limits after remeasurement, arrange an individual dose assessment.

Check the suspension concentration, dose in mg and volume in mL per dose. Compare the calculated dose with the maximum for the chosen regimen and confirm the volume can be measured accurately. Check the draft prescription before transferring it to the prescribing system.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen; Achtergrond; Doelgroep (verwijzing Kinderformularium)

Clindamycine (systemisch)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

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https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/clindamycine__systemisch_

Linked passages

  • Doseringen: endocarditisprofylaxe; waarschuwingen en voorzorgen; toedieningsvormen

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

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2025-12-18
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https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Prevention and prophylaxis; Table 1, p. S2–S3

NHG-Behandelrichtlijn Endocarditisprofylaxe

Nederlands Huisartsen Genootschap · auteursversie via NVMKA · Versie 1.0 · november 2016 · oorspronkelijke tekst; huidige NHG-webrevisie niet verifieerbaar

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2016-11
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https://www.nvmka.nl/wp-content/uploads/2022/07/2016-NHG-Behandelrichtlijn-Endocarditisprofylaxe-1.pdf

Linked passages

  • Medicamenteuze behandeling: Bij tandheelkundige behandeling, p. 6

Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document

European Academy of Paediatric Dentistry · 2025 · Eur Arch Paediatr Dent 26:1037–1043

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2025-10-03
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https://link.springer.com/article/10.1007/s40368-025-01068-9

Linked passages

  • Pulp infection, Tables 1–2; Antibiotic regimens; Antibiotic prophylaxis, Tables 6–7
  • Appendix 2: antibiotic prophylaxis for prevention of endocarditis

Kinderformularium · Amoxicilline

Nederlands Kenniscentrum Farmacotherapie bij Kinderen · Online monografie

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https://www.kinderformularium.nl/geneesmiddel/7/amoxicilline

Linked passages

  • Doseringen: Bacteriele infecties; Ernstige bacteriele infecties; Nierfunctiestoornissen
  • Doseringen: Endocarditis profylaxe, oraal

Kinderformularium · Clindamycine

Nederlands Kenniscentrum Farmacotherapie bij Kinderen · Online monografie

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https://www.kinderformularium.nl/geneesmiddel/312/clindamycine

Linked passages

  • Doseringen: Endocarditis profylaxe, oraal; beschikbare toedieningsvormen

Amoxicilline Centrient · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 117001 · 125 mg/5 mL en RVG 117002 · 250 mg/5 mL

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https://www.geneesmiddeleninformatiebank.nl/smpc/h117003_smpc.pdf

Linked passages

  • Rubrieken 2, 4.1–4.4 en 6.5–6.6

Dalacin C · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 06354 · 75 mg/5 mL

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https://www.geneesmiddeleninformatiebank.nl/smpc/h06354_smpc.pdf

Linked passages

  • Rubrieken 2, 4.1–4.4 en 6.5–6.6

Metric Units and the Preferred Dosing of Orally Administered Liquid Medications

American Academy of Pediatrics · Pediatrics 135(4):784–787 · 2015

Publication
2015-04-01
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https://publications.aap.org/pediatrics/article/135/4/e20150072/33600/Metric-Units-and-the-Preferred-Dosing-of-Orally

Linked passages

  • Recommendations 1–4 and 6–8

Richtlijn Elektronisch voorschrijven

KNMG en beroepsorganisaties, waaronder KNMT · 2013 · Richtlijn Elektronisch voorschrijven

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2013-09-01
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https://www.knmg.nl/download/richtlijn-elektronisch-voorschrijven-2

Linked passages

  • Artikel 1: recept; artikelen 2–4: voorschrijven en medicatiebewaking

SAS Program for CDC Growth Charts

Centers for Disease Control and Prevention · CDC 2000 · documentatie 2024

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2024-09-25
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https://www.cdc.gov/growth-chart-training/hcp/computer-programs/sas.html

Linked passages

  • Tabel 2: gewicht-naar-leeftijd; Extreme values, implausible values, and data errors

Automated Dose-Rounding Recommendations for Pediatric Medications

Johnson KB et al. · Pediatrics · 2011 · 128(2):e422–e428

Publication
2011-08-01
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https://pmc.ncbi.nlm.nih.gov/articles/PMC3387858/

Linked passages

  • Table 4: amoxicilline en clindamycine

2023 ESC Guidelines for the management of endocarditis

European Society of Cardiology · 2023 · European Heart Journal 44:3948–4042 · tabel 6

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2023-08-25
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https://academic.oup.com/eurheartj/article/44/39/3948/7243107

Linked passages

  • § 3.3.1 en tabel 6: profylaxe bij hoogrisico-tandheelkundige ingrepen, p. 3961

Zithromax 200 mg/5 mL, poeder voor orale suspensie

College ter Beoordeling van Geneesmiddelen · SmPC · RVG 14999

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2026-05-22
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https://www.geneesmiddeleninformatiebank.nl/smpc/h14999_smpc.pdf

Linked passages

  • Rubrieken 4.1 en 4.3–4.5: indicaties, QT-risico en interacties

Claritromycine Sandoz 125 mg/5 mL en 250 mg/5 mL, granulaat voor orale suspensie

College ter Beoordeling van Geneesmiddelen · SmPC · RVG 30849–30850

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https://www.geneesmiddeleninformatiebank.nl/smpc/h30849_smpc.pdf

Linked passages

  • Rubrieken 4.1 en 4.3–4.5: indicaties, QT-risico en interacties
an app by mondarium
AB Kader

Antibiotics in dental care

Acute pericoronitis · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Acute pericoronitis

Recognition and local treatment

Assess pain and swelling around a partially erupted tooth, usually a lower third molar. Inspect the operculum and check whether the opposing tooth is traumatising it. Assess mouth opening, spread of swelling and systemic symptoms.

Clean and irrigate the space under the operculum where accessible. Remove trapped debris and provide pain relief if needed. After the acute phase, assess whether the affected tooth can erupt or whether the tooth or the traumatising opposing tooth needs removal.

The NVMKA advises against surgical extraction in the acute phase. Simple extraction without bone removal may be considered if mouth opening is sufficient and anaesthesia adequate. In pseudopericoronitis caused by traumatic contact, the NVMKA recommends treating the offending opposing tooth during the acute phase.

When antibiotics or referral?

Inflammation confined to the operculum requires local treatment. Consider systemic antibiotics as an adjunct if there is general malaise or impending spread to a fascial space. If symptoms worsen or fail to improve, reassess for spread and consult an oral and maxillofacial surgeon if in doubt.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen; alarmsymptomen

Pericoronitis

Health Service Executive, Ierland · Versie 2.0 · lokale behandeling

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https://assets.hse.ie/media/documents/Pericoronitis_guideline.pdf#page=1

Linked passages

  • Comments on local measures: debridement and irrigation, p. 1

Pericoronitis

Nederlandse Vereniging voor Mondziekten, Kaak- en Aangezichtschirurgie · MKA-leidraad 1.3 · november 2025

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https://www.nvmka.nl/wp-content/uploads/2025-Pericoronitis-MKA-leidraad-1.3.pdf

Linked passages

  • Pericoronitis, p. 1
  • Diagnose; lokale therapie; verwijderen van de oorzaak, p. 1
  • Lokale therapie en indicatie voor antibiotica, p. 1
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AB Kader

Antibiotics in dental care

Dry socket after extraction · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Dry socket after extraction

Recognition

Consider dry socket if pain worsens one to three days after extraction and the socket has lost part or all of the clot. Bad breath can occur. Pain can be severe when the clot is completely absent.

Diagnosis is based on the clinical course and inspection of the socket. Take a radiograph if a retained root is suspected.

Local symptom relief

Consider gently irrigating the socket with lukewarm water or saline. Explain how to rinse locally at home and advise appropriate analgesia. If there is insufficient improvement, a temporary dressing may be considered after reassessment. Agree when it will be removed.

Pain can persist for several days despite these measures. Tell the patient when to contact the practice, especially if symptoms worsen or new swelling or fever develops.

Antibiotics for wound infection

Antibiotics are not indicated for dry socket without concurrent infection. The NVMKA found no evidence of a therapeutic benefit.

If pus, increasing swelling or fever occurs, assess for postoperative wound infection and determine whether local source control is needed. If infection is spreading or systemic signs are present, follow the guidance for odontogenic infection and assess urgency.

Sources

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen; uitbreiding en alarmsymptomen
  • Aanbevelingen; beoordeling op uitbreiding en alarmsymptomen

Alveolitis

Nederlandse Vereniging voor Mondziekten, Kaak- en Aangezichtschirurgie · MKA-leidraad 2.0 · november 2025

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https://www.nvmka.nl/wp-content/uploads/2025-Alveolitis-MKA-leidraad-2.0.pdf

Linked passages

  • Alveolitis, p. 1–2
  • Terminologie; diagnose, p. 1
  • Behandeling, p. 1–2
an app by mondarium
AB Kader

Antibiotics in dental care

Joint prosthesis · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Prophylaxis

Joint prosthesis

No prophylaxis for joint prosthesis

A joint prosthesis, such as a hip or knee replacement, does not indicate antibiotics before a dental procedure to prevent haematogenous prosthetic joint infection. The NOV and KNMT state that this also applies to patients with impaired immunity.

Assess any separate indication, such as endocarditis prophylaxis, against the relevant guideline. Advise good oral hygiene and regular dental check-ups.

Sources

Antibioticaprofylaxe bij tandheelkundige ingrepen bij patiënten met een gewrichtsprothese

Nederlandse Orthopaedische Vereniging en Koninklijke Nederlandse Maatschappij tot bevordering der Tandheelkunde · Richtlijnmodule · 2016

Publication
2016-02-16
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2026-11-11
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https://richtlijnendatabase.nl/richtlijn/antibioticaprofylaxe_bij_gewrichtsprothese/antibioticaprofylaxe_bij_gewrichtsprothese.html

Linked passages

  • Antibioticaprofylaxe bij gewrichtsprothese
  • Aanbevelingen 1–3
an app by mondarium
AB Kader

Antibiotics in dental care

Tooth injury: avulsion and replantation · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Treatment

Tooth injury: avulsion and replantation

Immediate care

In avulsion, the tooth is completely displaced from its socket. Arrange immediate dental care. The KNMT aims for assessment within 30 to 60 minutes. Check whether the tooth is permanent or primary. Do not replant a primary tooth.

Hold a permanent tooth by the crown only. If visibly contaminated, rinse it briefly and gently without touching or scrubbing the root. Replant as soon as possible if safe and feasible. If immediate replantation is not possible, keep the tooth in milk for transport.

Replantation, splinting and follow-up

Record the time out of the mouth, the time the tooth was dry and the storage medium. Assess root development, the socket and any associated injuries. After replantation, confirm the tooth's position clinically and radiographically.

The Dutch splinting instructions usually advise a flexible splint for three weeks after avulsion. Adapt the splinting plan if there is additional alveolar injury. Plan clinical and radiographic follow-up, and decide on endodontic management based on root development and healing.

Antibiotics and tetanus

Assess contamination of the tooth and wound. KIMO notes that the Dutch Dental Trauma Guide reserves immediate systemic antibiotics for signs of contamination. Follow the injury-specific protocol for the indication and choice of medicine.

Check tetanus vaccination status. If in doubt, consult the doctor about the tetanus prophylaxis required.

Sources

Tandletsel – Dental Trauma Guide

KIMO – Kennisinstituut Mondzorg · Nederlandse uitgave · 2025

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https://www.hetkimo.nl/richtlijnen/dtg/over-de-dental-trauma-guide/

Linked passages

  • Tandletsel – Dental Trauma Guide
  • Belangrijkste wijzigingen in de Nederlandse versie; follow-up
  • Belangrijkste wijzigingen in de Nederlandse versie; Antibioticabeleid

Beoordeling van spoed bij tandheelkundige spoedgevallen

Koninklijke Nederlandse Maatschappij tot bevordering der Tandheelkunde · Online praktijkrichtlijn

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https://knmt.nl/praktijkzaken/regelen-rond-kwaliteit-en-klachten/opvang-tandheelkundige-spoedgevallen/beoordeling-van-spoed

Linked passages

  • Bij avulsie of ander ernstig tandletsel

Tand eruit? Tand erin!

KNMT · Alles over het gebit · Online instructie voor eerste hulp bij tandletsel

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https://www.allesoverhetgebit.nl/alles-over-mondgezondheid/aandoeningen/tand-eruit-tand-erin

Linked passages

  • Spoelen, terugplaatsen en verschil tussen melkgebit en blijvend gebit

Spalkinstructie Dental Trauma Guide

KIMO – Kennisinstituut Mondzorg · Nederlandse instructie · 2025

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https://www.hetkimo.nl/wp-content/uploads/2025/04/Spalkinstructie-KIMO-v2.pdf#page=3

Linked passages

  • Controle na spalken; spalkduur; flexibele spalk, p. 3

Guidelines for the Management of Traumatic Dental Injuries: 2. Avulsion of Permanent Teeth

International Association of Dental Traumatology · Dental Traumatology · 2020 · onderzoek, follow-up en tetanus

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https://www.aapd.org/globalassets/media/policies_guidelines/e_avulsion.pdf

Linked passages

  • Beoordeling van droogtijd en apicale ontwikkeling; klinische en radiologische follow-up
  • Paragraaf 7: Tetanus
an app by mondarium
AB Kader

Antibiotics in dental care

Azithromycin · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Azithromycin

Paediatric endocarditis prophylaxis

Azithromycin is a macrolide. The EAPD lists it as an alternative for confirmed penicillin allergy when a child with a high-risk cardiac condition undergoes a high-risk dental procedure. Use it only after consulting the paediatric cardiologist. Its use for endocarditis prophylaxis is off-label.

The EAPD regimen is a single oral dose of 15 mg/kg, 30 to 60 minutes before the procedure. The ESC sets a maximum of 500 mg per dose. See Paediatric antibiotics for indications and other prophylactic regimens.

The calculator uses 200 mg/5 mL (40 mg/mL) from 6 months of age and for weights below 45 kg. At 45 kg or above, have the paediatric cardiologist and pharmacist confirm the formulation and dose.

QT risk and interactions

Assess QT prolongation, electrolyte disturbances and concomitant medicines that prolong the QT interval. Seek individual assessment if there is significant hepatic or renal impairment.

Sources

Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document

European Academy of Paediatric Dentistry · 2025 · Eur Arch Paediatr Dent 26:1037–1043

Publication
2025-10-03
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://link.springer.com/article/10.1007/s40368-025-01068-9

Linked passages

  • Appendix 2: antibiotic prophylaxis for prevention of endocarditis

2023 ESC Guidelines for the management of endocarditis

European Society of Cardiology · 2023 · European Heart Journal 44:3948–4042 · tabel 6

Publication
2023-08-25
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://academic.oup.com/eurheartj/article/44/39/3948/7243107

Linked passages

  • § 3.3.1 en tabel 6: profylaxe bij hoogrisico-tandheelkundige ingrepen, p. 3961

Zithromax 200 mg/5 mL, poeder voor orale suspensie

College ter Beoordeling van Geneesmiddelen · SmPC · RVG 14999

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Niet vermeld
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2026-05-22
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h14999_smpc.pdf

Linked passages

  • Rubrieken 2, 4.1–4.5 en 6.5–6.6: sterkte, indicaties, contra-indicaties, interacties en doseerhulpmiddel
an app by mondarium
AB Kader

Antibiotics in dental care

Clarithromycin · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Medicine information

Clarithromycin

Paediatric endocarditis prophylaxis

Clarithromycin is a macrolide. The EAPD lists it as an alternative for confirmed penicillin allergy when a child with a high-risk cardiac condition undergoes a high-risk dental procedure. Use it only after consulting the paediatric cardiologist. Its use for endocarditis prophylaxis is off-label.

The EAPD regimen is a single oral dose of 15 mg/kg, 30 to 60 minutes before the procedure. The ESC sets a maximum of 500 mg per dose. See Paediatric antibiotics for indications and other prophylactic regimens.

The calculator uses the 125 mg/5 mL (25 mg/mL) suspension from 6 months of age. Check the strength: the 250 mg/5 mL suspension requires a different volume.

QT risk and interactions

Clarithromycin is contraindicated with known QT prolongation, previous ventricular arrhythmia, hypokalaemia or hypomagnesaemia. Check for CYP3A4 interactions, including with oral midazolam and ivabradine. Seek individual assessment if there is significant renal or hepatic impairment.

Sources

Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document

European Academy of Paediatric Dentistry · 2025 · Eur Arch Paediatr Dent 26:1037–1043

Publication
2025-10-03
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://link.springer.com/article/10.1007/s40368-025-01068-9

Linked passages

  • Appendix 2: antibiotic prophylaxis for prevention of endocarditis

2023 ESC Guidelines for the management of endocarditis

European Society of Cardiology · 2023 · European Heart Journal 44:3948–4042 · tabel 6

Publication
2023-08-25
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://academic.oup.com/eurheartj/article/44/39/3948/7243107

Linked passages

  • § 3.3.1 en tabel 6: profylaxe bij hoogrisico-tandheelkundige ingrepen, p. 3961

Claritromycine Sandoz 125 mg/5 mL en 250 mg/5 mL, granulaat voor orale suspensie

College ter Beoordeling van Geneesmiddelen · SmPC · RVG 30849–30850

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2024-05-01
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h30849_smpc.pdf

Linked passages

  • Rubrieken 2, 4.1–4.5 en 6.5–6.6: sterkte, indicaties, contra-indicaties, interacties en doseerhulpmiddel
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Algemene principes van rationeel antibioticumgebruik

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · richtlijntekst 3 maart 2025

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/algemene-principes-van-rationeel-antibioticumgebruik/

Linked passages

  • Algemene principes van rationeel antibioticumgebruik
  • Indicatie voor antibiotica; Empirische therapie; Profylaxe
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Dentogene infecties en/of abces

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 7

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https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/dentogene-infecties-en-of-abces/

Linked passages

  • Aanbevelingen
  • Uitgangsvraag 7; Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond: alarmsymptomen en verwijzing
  • Aanbevelingen; uitgezonderde patiëntgroepen
  • Aanbevelingen: eerste keuze en MKA-overleg
  • Aanbevelingen; Achtergrond; Doelgroep (verwijzing Kinderformularium)
  • Aanbevelingen; alarmsymptomen
  • Aanbevelingen; uitbreiding en alarmsymptomen
  • Aanbevelingen; beoordeling op uitbreiding en alarmsymptomen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Periapicaal granuloom/parodontitis apicalis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 6

Publication
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Revised
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Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/therapeutisch-antibioticumgebruik-periapicaal-granuloom-parodontitis-apicalis/

Linked passages

  • Uitgangsvraag 6; Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond
  • Aanbevelingen; uitgezonderde patiëntgroepen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Endodontologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 2

Publication
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Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/antibioticaprofylaxe-endodontologie/

Linked passages

  • Uitgangsvraag 2; PICO; Aanbevelingen; Achtergrond
  • Aanbevelingen; Achtergrond
  • PICO: uitgezonderde patiëntgroepen; immuuncompromittering wordt door behandelende beroepsgroepen beoordeeld
  • PICO: immuuncompromittering
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Amoxicilline

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

Publication
Niet vermeld
Revised
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Accessed
2026-11-10
Open official source (new tab)

https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/a/amoxicilline

Linked passages

  • Contra-indicaties
  • Volledige preparaattekst; Contra-indicaties; Interacties; Doseringen
  • Contra-indicaties; Interacties; Doseringen; Zwangerschap; Lactatie
  • Waarschuwingen en voorzorgen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Clindamycine (systemisch)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/clindamycine__systemisch_

Linked passages

  • Waarschuwingen en voorzorgen
  • Volledige systemische preparaattekst; Contra-indicaties; Interacties; Waarschuwingen en voorzorgen
  • Contra-indicaties; Interacties; Waarschuwingen en voorzorgen; Zwangerschap; Lactatie
  • Waarschuwingen en voorzorgen; Interacties
  • Waarschuwingen en voorzorgen: Overgevoeligheid
  • Doseringen: endocarditisprofylaxe; waarschuwingen en voorzorgen; toedieningsvormen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Parodontitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 4

Publication
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Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/therapeutisch-antibioticumgebruik-parodontitis/

Linked passages

  • Aanbevelingen
  • Uitgangsvraag 4; Aanbevelingen
  • Aanbevelingen; uitgezonderde patiëntgroepen
  • Aanbevelingen: monokuur en complexe situaties
  • Aanbevelingen: complexe situaties
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Implantologie

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 1

Publication
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Revised
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Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/uitgangsvraag-1/

Linked passages

  • Aanbevelingen
  • Uitgangsvraag 1; Aanbevelingen; Achtergrond
  • PICO: uitgesloten patiëntgroepen
  • Aanbevelingen; Achtergrond: timing en verlengde profylaxe
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Preventie van MRONJ

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 8

Publication
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Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/preventie-van-mronj-patienten-met-botafbraakremmende-medicatie-of-angiogeneseremmers/

Linked passages

  • Aanbevelingen
  • Uitgangsvraag 8; PICO; Aanbevelingen
  • Aanbevelingen: ingreep en blootstellingsduur
  • Aanbevelingen; Achtergrond: botafbraakremmende medicatie
  • Aanbevelingen: middelkeuze en ontbreken doseringsconsensus
  • PICO: radiotherapie, immuuncompromittering en endocarditisprofylaxe afzonderlijk beoordeeld
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Derde molaar

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 3 · verwijsmodule

Publication
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Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/antibioticaprofylaxe-derde-molaar/

Linked passages

  • Uitgangsvraag 3: verwijzing
  • Verwijzing naar richtlijn Derde molaar
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Derde molaar — Nazorg

KIMO — Kennisinstituut Mondzorg · Richtlijn 2020 · §5.1 Antibiotica

Publication
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Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/derde-molaar/nazorg/

Linked passages

  • Nazorg 5.1 Antibiotica
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Indicatiestelling antibioticumgebruik in de mondzorg — Peri-implantitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2025 · uitgangsvraag 5 · verwijsmodule

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/indicatiestelling-antibioticagebruik-in-de-mondzorg/therapeutisch-antibioticumgebruik-peri-implantitis/

Linked passages

  • Uitgangsvraag 5: verwijzing
  • Verwijzing naar richtlijn Peri-implantaire infecties
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Peri-implantaire infecties — behandeling van mucositis en peri-implantitis

KIMO — Kennisinstituut Mondzorg · Richtlijn 2018 · richtlijnsamenvatting 4 en 5

Publication
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Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/peri-implantaire-mucositis-en-peri-implantitis/introductie/

Linked passages

  • Richtlijnsamenvatting 4 en 5
  • Richtlijnsamenvatting 4 en 5: niet-chirurgische en chirurgische behandeling
  • Richtlijnsamenvatting 5
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

2023 ESC guidelines for the management of infective endocarditis — Statement of endorsement by the NVVC, full version

NVVC · Netherlands Heart Journal · Neth Heart J 2026;34(Suppl 1):S1–S13 · online 18 december 2025 · DOI 10.1007/s12471-025-02010-w

Publication
2025-12-18
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://pure.umcutrecht.nl/ws/files/705565154/s12471-025-02010-w.pdf

Linked passages

  • Prevention and prophylaxis; Table 1, p. S2–S3
  • Prevention and prophylaxis: high-risk versus intermediate-risk, p. S2
  • Prevention and prophylaxis, p. S2–S3
  • Table 1; toelichting Nederlandse afwijking van ESC 2023, p. S3
  • Table 1 en begeleidende tekst, p. S3
  • Table 1, p. S3
  • Table 1 en toelichting, p. S3
  • Table 1: Revised prophylactic antibiotic regime for high-risk dental procedures, p. S3
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

NHG-Behandelrichtlijn Endocarditisprofylaxe

Nederlands Huisartsen Genootschap · auteursversie via NVMKA · Versie 1.0 · november 2016 · oorspronkelijke tekst; huidige NHG-webrevisie niet verifieerbaar

Publication
2016-11
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.nvmka.nl/wp-content/uploads/2022/07/2016-NHG-Behandelrichtlijn-Endocarditisprofylaxe-1.pdf

Linked passages

  • Risicopatiënten, ingrepen en orale timing, p. 4–6
  • Hoogrisicopatiënten en hoogrisico-ingrepen; Geen indicaties, p. 4–5
  • Medicamenteuze behandeling: Bij tandheelkundige behandeling, p. 6
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Extramurale mondzorg tijdens en na kankerbehandeling

KIMO — Kennisinstituut Mondzorg · In werking 15 juni 2026 · PDF-tekst 28 maart 2025 · KNMT-aanvaarding 20 april 2026

Publication
2026-06-15
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.hetkimo.nl/wp-content/uploads/2026/06/KPR-EMK-richtlijn-28032025.pdf

Linked passages

  • Algemene aspecten; Tabel 1, p. 16–17
  • MRONJ: medicatie en toedieningswegen, p. 28–30
  • Algemene aspecten; Tabel 1; Hoofd-halsradiotherapie, p. 16–17, 35–36
  • Algemene aspecten: aandachtspunten; Tabel 1 en toelichting, p. 16–17
  • Hoofd-halsradiotherapie: aandachtspunten en aanbeveling, p. 35–36
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Metronidazol (oraal)

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/m/metronidazol__oraal_

Linked passages

  • Interacties
  • Volledige orale preparaattekst; Contra-indicaties; Interacties; Waarschuwingen en voorzorgen
  • Contra-indicaties; Interacties; Waarschuwingen en voorzorgen; Zwangerschap; Lactatie
  • Waarschuwingen en voorzorgen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Amoxicilline/clavulaanzuur

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/a/amoxicilline_clavulaanzuur

Linked passages

  • Volledige preparaattekst; Advies; Indicaties; Contra-indicaties; Interacties
  • Advies; Indicaties; Doseringen: algemeen bij infecties
  • Advies; Indicaties
  • Contra-indicaties; Interacties; Doseringen; Waarschuwingen en voorzorgen
  • Waarschuwingen en voorzorgen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Ceftriaxon

Zorginstituut Nederland — Farmacotherapeutisch Kompas · Dynamische preparaattekst · geen afzonderlijke revisiedatum vermeld

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-10
Open official source (new tab)

https://www.farmacotherapeutischkompas.nl/bladeren/preparaatteksten/c/ceftriaxon

Linked passages

  • Contra-indicaties
  • Volledige preparaattekst; Contra-indicaties; Interacties; Waarschuwingen en voorzorgen
  • Contra-indicaties; Interacties; Doseringen: Toediening; Waarschuwingen en voorzorgen
  • Waarschuwingen en voorzorgen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Best clinical practise guidance for the use of antibiotics in children: an EAPD policy document

European Academy of Paediatric Dentistry · 2025 · Eur Arch Paediatr Dent 26:1037–1043

Publication
2025-10-03
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://link.springer.com/article/10.1007/s40368-025-01068-9

Linked passages

  • Pulp infection, Tables 1–2; Antibiotic regimens; Antibiotic prophylaxis, Tables 6–7
  • Appendix 2: antibiotic prophylaxis for prevention of endocarditis
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Kinderformularium · Amoxicilline

Nederlands Kenniscentrum Farmacotherapie bij Kinderen · Online monografie

Publication
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Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.kinderformularium.nl/geneesmiddel/7/amoxicilline

Linked passages

  • Doseringen: Bacteriele infecties; Ernstige bacteriele infecties; Nierfunctiestoornissen
  • Doseringen: Endocarditis profylaxe, oraal
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Kinderformularium · Clindamycine

Nederlands Kenniscentrum Farmacotherapie bij Kinderen · Online monografie

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.kinderformularium.nl/geneesmiddel/312/clindamycine

Linked passages

  • Doseringen: Endocarditis profylaxe, oraal; beschikbare toedieningsvormen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Amoxicilline Centrient · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 117001 · 125 mg/5 mL en RVG 117002 · 250 mg/5 mL

Publication
Niet vermeld
Revised
2023-06-15
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h117003_smpc.pdf

Linked passages

  • Rubrieken 2, 4.1–4.4 en 6.5–6.6
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Dalacin C · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 06354 · 75 mg/5 mL

Publication
Niet vermeld
Revised
2026-07-10
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h06354_smpc.pdf

Linked passages

  • Rubrieken 2, 4.1–4.4 en 6.5–6.6
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Metric Units and the Preferred Dosing of Orally Administered Liquid Medications

American Academy of Pediatrics · Pediatrics 135(4):784–787 · 2015

Publication
2015-04-01
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://publications.aap.org/pediatrics/article/135/4/e20150072/33600/Metric-Units-and-the-Preferred-Dosing-of-Orally

Linked passages

  • Recommendations 1–4 and 6–8
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Richtlijn Elektronisch voorschrijven

KNMG en beroepsorganisaties, waaronder KNMT · 2013 · Richtlijn Elektronisch voorschrijven

Publication
2013-09-01
Revised
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Accessed
2026-11-11
Open official source (new tab)

https://www.knmg.nl/download/richtlijn-elektronisch-voorschrijven-2

Linked passages

  • Artikel 1: recept; artikelen 2–4: voorschrijven en medicatiebewaking
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Augmentin 500 mg/125 mg, filmomhulde tabletten · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 09840

Publication
Niet vermeld
Revised
2026-09-09
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h09840_smpc.pdf

Linked passages

  • Rubrieken 4.1–4.4: indicaties, dosering, behandelduur, nierfunctie en contra-indicaties
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Ceftriaxon Navamedic 1 g · Samenvatting van de productkenmerken

College ter Beoordeling van Geneesmiddelen · RVG 134134 · 1 g, poeder voor oplossing voor injectie/infusie

Publication
Niet vermeld
Revised
2026-09-11
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h134135_smpc.pdf

Linked passages

  • Rubrieken 4.1–4.4 en 6.5–6.6: geregistreerde indicaties, intraveneuze toediening, contra-indicaties en flacon
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Spoedlijst bij Beleid rondom spoedoperaties · MKA-chirurgie

Nederlandse Vereniging voor Mond-, Kaak- en Aangezichtschirurgie · 2024 · Bijlage 5

Publication
2024-09-04
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.nvmka.nl/wp-content/uploads/2024-Bijlage_Spoedlijst_5__NVMKA_Nederlandse_Vereniging_voor_Mond-_Kaak-_en_Aangezichtschirurgie.pdf

Linked passages

  • Categorie 1: snel progressief logeabces met bedreigde luchtweg
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

SAS Program for CDC Growth Charts

Centers for Disease Control and Prevention · CDC 2000 · documentatie 2024

Publication
2024-09-25
Revised
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Accessed
2026-11-11
Open official source (new tab)

https://www.cdc.gov/growth-chart-training/hcp/computer-programs/sas.html

Linked passages

  • Tabel 2: gewicht-naar-leeftijd; Extreme values, implausible values, and data errors
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Automated Dose-Rounding Recommendations for Pediatric Medications

Johnson KB et al. · Pediatrics · 2011 · 128(2):e422–e428

Publication
2011-08-01
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://pmc.ncbi.nlm.nih.gov/articles/PMC3387858/

Linked passages

  • Table 4: amoxicilline en clindamycine
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Essential messages from the 2023 ESC Guidelines for the management of endocarditis

European Society of Cardiology · ESC 2023 · Essential messages

Publication
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Accessed
2026-11-11
Open official source (new tab)

https://www.escardio.org/static-file/Escardio/Guidelines/Products/Slide%20sets/2023%20Gls/Essential%20Messages_2023%20Endocarditis.pdf

Linked passages

  • Key messages, punt 1: hoogrisicogroepen en profylaxe bij oro-dentale ingrepen
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Pericoronitis

Health Service Executive, Ierland · Versie 2.0 · lokale behandeling

Publication
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Revised
2023-11
Accessed
2026-11-11
Open official source (new tab)

https://assets.hse.ie/media/documents/Pericoronitis_guideline.pdf#page=1

Linked passages

  • Comments on local measures: debridement and irrigation, p. 1
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Pericoronitis

Nederlandse Vereniging voor Mondziekten, Kaak- en Aangezichtschirurgie · MKA-leidraad 1.3 · november 2025

Publication
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Revised
2025-11
Accessed
2026-11-11
Open official source (new tab)

https://www.nvmka.nl/wp-content/uploads/2025-Pericoronitis-MKA-leidraad-1.3.pdf

Linked passages

  • Pericoronitis, p. 1
  • Diagnose; lokale therapie; verwijderen van de oorzaak, p. 1
  • Lokale therapie en indicatie voor antibiotica, p. 1
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Alveolitis

Nederlandse Vereniging voor Mondziekten, Kaak- en Aangezichtschirurgie · MKA-leidraad 2.0 · november 2025

Publication
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Revised
2025-11
Accessed
2026-11-11
Open official source (new tab)

https://www.nvmka.nl/wp-content/uploads/2025-Alveolitis-MKA-leidraad-2.0.pdf

Linked passages

  • Alveolitis, p. 1–2
  • Terminologie; diagnose, p. 1
  • Behandeling, p. 1–2
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Antibioticaprofylaxe bij tandheelkundige ingrepen bij patiënten met een gewrichtsprothese

Nederlandse Orthopaedische Vereniging en Koninklijke Nederlandse Maatschappij tot bevordering der Tandheelkunde · Richtlijnmodule · 2016

Publication
2016-02-16
Revised
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Accessed
2026-11-11
Open official source (new tab)

https://richtlijnendatabase.nl/richtlijn/antibioticaprofylaxe_bij_gewrichtsprothese/antibioticaprofylaxe_bij_gewrichtsprothese.html

Linked passages

  • Antibioticaprofylaxe bij gewrichtsprothese
  • Aanbevelingen 1–3
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Richtlijn endodontische diagnostiek en behandeling

Nederlandse Vereniging voor Endodontologie · Update 2025 · versie 1.0

Publication
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Revised
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Accessed
2026-11-11
Open official source (new tab)

https://nvve.com/wp-content/uploads/2026/08/Richtlijn-Endodontische-Diagnostiek-en-Behandeling-update-2025_v1.0.pdf#page=221

Linked passages

  • Hoofdstuk 9: Acute klachten en pijnmanagement; Aanbevelingen, p. 220
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Tandletsel – Dental Trauma Guide

KIMO – Kennisinstituut Mondzorg · Nederlandse uitgave · 2025

Publication
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Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.hetkimo.nl/richtlijnen/dtg/over-de-dental-trauma-guide/

Linked passages

  • Tandletsel – Dental Trauma Guide
  • Belangrijkste wijzigingen in de Nederlandse versie; follow-up
  • Belangrijkste wijzigingen in de Nederlandse versie; Antibioticabeleid
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Beoordeling van spoed bij tandheelkundige spoedgevallen

Koninklijke Nederlandse Maatschappij tot bevordering der Tandheelkunde · Online praktijkrichtlijn

Publication
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Revised
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Accessed
2026-11-11
Open official source (new tab)

https://knmt.nl/praktijkzaken/regelen-rond-kwaliteit-en-klachten/opvang-tandheelkundige-spoedgevallen/beoordeling-van-spoed

Linked passages

  • Bij avulsie of ander ernstig tandletsel
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Tand eruit? Tand erin!

KNMT · Alles over het gebit · Online instructie voor eerste hulp bij tandletsel

Publication
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Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.allesoverhetgebit.nl/alles-over-mondgezondheid/aandoeningen/tand-eruit-tand-erin

Linked passages

  • Spoelen, terugplaatsen en verschil tussen melkgebit en blijvend gebit
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Spalkinstructie Dental Trauma Guide

KIMO – Kennisinstituut Mondzorg · Nederlandse instructie · 2025

Publication
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Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.hetkimo.nl/wp-content/uploads/2025/04/Spalkinstructie-KIMO-v2.pdf#page=3

Linked passages

  • Controle na spalken; spalkduur; flexibele spalk, p. 3
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Guidelines for the Management of Traumatic Dental Injuries: 2. Avulsion of Permanent Teeth

International Association of Dental Traumatology · Dental Traumatology · 2020 · onderzoek, follow-up en tetanus

Publication
Niet vermeld
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://www.aapd.org/globalassets/media/policies_guidelines/e_avulsion.pdf

Linked passages

  • Beoordeling van droogtijd en apicale ontwikkeling; klinische en radiologische follow-up
  • Paragraaf 7: Tetanus
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

2023 ESC Guidelines for the management of endocarditis

European Society of Cardiology · 2023 · European Heart Journal 44:3948–4042 · tabel 6

Publication
2023-08-25
Revised
Niet vermeld
Accessed
2026-11-11
Open official source (new tab)

https://academic.oup.com/eurheartj/article/44/39/3948/7243107

Linked passages

  • § 3.3.1 en tabel 6: profylaxe bij hoogrisico-tandheelkundige ingrepen, p. 3961
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Zithromax 200 mg/5 mL, poeder voor orale suspensie

College ter Beoordeling van Geneesmiddelen · SmPC · RVG 14999

Publication
Niet vermeld
Revised
2026-05-22
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h14999_smpc.pdf

Linked passages

  • Rubrieken 4.1 en 4.3–4.5: indicaties, QT-risico en interacties
  • Rubrieken 2, 4.1–4.5 en 6.5–6.6: sterkte, indicaties, contra-indicaties, interacties en doseerhulpmiddel
an app by mondarium
AB Kader

Sources · Version 0.3.6 · Bijgewerkt 2026-11-11

Antibiotic treatment and prophylaxis in dental care, with dosing regimens for adults and children and information on risk groups and medicines.

Assess the indication, age and patient-specific risks before choosing a regimen. Weight-based calculation applies only to the selected paediatric regimen. Use the relevant product information to check allergies, renal and hepatic function, interactions, pregnancy and breastfeeding.

Claritromycine Sandoz 125 mg/5 mL en 250 mg/5 mL, granulaat voor orale suspensie

College ter Beoordeling van Geneesmiddelen · SmPC · RVG 30849–30850

Publication
Niet vermeld
Revised
2024-05-01
Accessed
2026-11-11
Open official source (new tab)

https://www.geneesmiddeleninformatiebank.nl/smpc/h30849_smpc.pdf

Linked passages

  • Rubrieken 4.1 en 4.3–4.5: indicaties, QT-risico en interacties
  • Rubrieken 2, 4.1–4.5 en 6.5–6.6: sterkte, indicaties, contra-indicaties, interacties en doseerhulpmiddel
an app by mondarium