Paracetamol / ibuprofen
500/150 mg example for adults.
Prescription optionsCheck the strength
AFTPharm contains 500/150 mg paracetamol/ibuprofen and Nuralgan 500/200 mg. Consult the product information for the strength selected.
Check for duplicate dosing
Include paracetamol from all products , including over-the-counter medicines and combination products. Check weight, nutritional status, liver function and duration of use.
Prescription options
Draft for your prescribing system. Check patient details, contraindications and medication safety before prescribing.
Paracetamol/ibuprofen 500/150 mg
Fixed combination for short-term mild to moderate pain in suitable adults 50 kg or above if one medicine is insufficient. This applies only to the specified AFTPharm strength.
Checks before prescribing
This standard regimen is unsuitable in hepatic impairment or Gilbert syndrome. In severe hepatic failure or active alcoholism, AFTPharm is contraindicated. KIMO advises against NSAID use after a dental procedure that causes bleeding in patients taking antithrombotics, even if antithrombotic therapy has been temporarily interrupted. Discuss over-the-counter NSAIDs as well. See When taking antithrombotics. Check gastrointestinal, renal and cardiovascular risk factors, pregnancy, hypersensitivity and interactions. Do not combine two NSAIDs. See Frailty, kidney or liver impairment. Use this instead of taking paracetamol and ibuprofen separately. Do not add a paracetamol-containing medicine. Use the lowest effective dose.
R/ Paracetamol/ibuprofen 500/150 mg film-coated tablet (AFTPharm)
- Per dose
- 1 to 2 tablets by mouth (500 to 1,000 mg / 150 to 300 mg)
- Frequency and interval in this example
- If necessary, at least 6 hours between intakes
- Maximum per 24 hours
- 6 tablets (3,000 mg of paracetamol and 900 mg of ibuprofen)
- Quantity in this draft
- Maximum 18 tablets
Maximum duration of use: 3 days. Stop earlier if the medicine is no longer needed. Reassess if pain relief is inadequate or pain worsens.
Sources for this topic
Reference for dentists on acute dental pain and pain after treatment.
- Farmacotherapeutisch Kompas · Nuralgan 500/200 mg (paracetamol/ibuprofen) · Samenstelling, dosering en voorzorgen voor 500/200 mg
- College ter Beoordeling van Geneesmiddelen · Paracetamol/Ibuprofen AFTPharm 500/150 mg · RVG 117254 · SmPC §2 en §4.2–4.5
- Farmacotherapeutisch Kompas · Paracetamol · Doseringen, interacties en waarschuwingen
- Farmacotherapeutisch Kompas · Ibuprofen (systemisch) · Contra-indicaties, interacties en zwangerschap
- KIMO · Bloedige ingrepen in de mondzorg bij patiënten die antitrombotica gebruiken · Versie 2025 · uitgangsvraag 5, NSAID-beleid
- KNMG en betrokken beroepsverenigingen · Elektronisch voorschrijven · Artikelen 2 en 3 · medicatiebewaking
