Pain around a wisdom tooth
Pericoronitis around a partially erupted molar.
Prescription optionsLocal treatment
Assess the tissues around the partially erupted tooth and the extent of involvement. SDCEP recommends starting with local rinsing and professional cleaning.
Pain relief alongside local care
For mild to moderate pain due to local pericoronitis, paracetamol is a first option. If pain relief is inadequate, adults may consider ibuprofen if an NSAID is appropriate.
If swelling increases or there is difficulty swallowing, follow the pathway for Swelling and infection.
Prescription options
Drafts for adults. Check the indication, contraindications and current medicines before prescribing.
Paracetamol aloneFirst option in mild to moderate pain in addition to local care
First option for acute nociceptive pain. This example applies to adults weighing more than 55 kg without risk factors for hepatotoxicity.
Checks before prescribing
Include all paracetamol from over-the-counter and combination products. Adjust the dose if there are risk factors.
R/ Paracetamol 500 mg tablet
- Per dose
- 1,000 mg by mouth (2 tablets)
- Frequency and interval in this example
- If necessary up to 3 times a day, approximately 8 hours between intakes
- Maximum per 24 hours
- 3,000 mg (6 tablets)
- Quantity in this draft
- Maximum 12 tablets
Duration in this example: 2 days. Stop earlier if the medicine is no longer needed. Reassess if pain relief is inadequate or pain worsens.
Ibuprofen aloneIf paracetamol is not effective, if NSAID is appropriate
Adults with toothache, if an NSAID is appropriate
Checks before prescribing
KIMO advises against NSAID use after a dental procedure that causes bleeding in patients taking antithrombotics, even if antithrombotic therapy has been temporarily interrupted. Discuss over-the-counter NSAIDs as well. See When taking antithrombotics. Check gastrointestinal, renal and cardiovascular risk factors, pregnancy, hypersensitivity and interactions. Do not combine two NSAIDs. See Frailty, kidney or liver impairment.
R/ Ibuprofen 400 mg film-coated tablet (Spidifen)
- Per dose
- 400 mg by mouth (1 tablet)
- Frequency and interval in this example
- If necessary up to 3 times a day, approximately 8 hours between intakes
- Spidifen SmPC §4.2: every 4 to 6 hours if necessary.
- Maximum per 24 hours
- 1,200 mg (3 tablets)
- Quantity in this draft
- Maximum 6 tablets
Duration in this example: 2 days. Stop earlier if the medicine is no longer needed. Reassess if pain relief is inadequate or pain worsens.
Sources for this topic
Reference for dentists on acute dental pain and pain after treatment.
- SDCEP · Acute periodontal conditions · local measures · Pericoronitis · lokale behandeling
- SDCEP · Acute pericoronitis · Initial management · pijnstilling en beoordeling van uitbreiding
- Farmacotherapeutisch Kompas · Pijn · Advies en stappenplan bij acute nociceptieve pijn
- NVvE · Richtlijn endodontische diagnostiek en behandeling · Update 2025 v1.0 · hoofdstuk 9, p. 219–222
- Farmacotherapeutisch Kompas · Paracetamol · Doseringen, interacties en waarschuwingen
- CBG · Paracetamol PharmaMatch 500 mg · RVG 109490 · SmPC §4.2–4.5
- CBG · Spidifen 400 mg, tabletten · RVG 25385 · SmPC §4.1–4.5
- Farmacotherapeutisch Kompas · NSAID’s, systemisch · Typerende bijwerkingen, toepasbaarheid en interacties
- KIMO · Bloedige ingrepen in de mondzorg bij patiënten die antitrombotica gebruiken · Versie 2025 · uitgangsvraag 5, NSAID-beleid
- KNMG en betrokken beroepsverenigingen · Elektronisch voorschrijven · Artikelen 2 en 3 · medicatiebewaking
